Baraclude is a new antiviral prescription drug used for chronic infection with the hepatitis B virus (HBV) in adults who also have active liver damage.

What is Hepatitis B?

Hepatitis B is a disease of the liver caused by the Hepatitis z virus (HBV), a member of the Hepadnavirus family and one of several unrelated viral species which cause viral hepatitis. Symptoms of the acute illness caused by the virus include liver inflammation, vomiting, jaundice, and rarely, death. Chronic hepatitis B may cause liver cirrhosis which may then lead to liver cancer.

Hepatitis B is largely transmitted through exposure to bodily fluids containing the virus. This includes unprotected sexual contact, blood transfusions, re-use of contaminated needles and syringes, vertical transmission from mother to child during childbirth, and so on.

What should I know about Baraclude before using it?

• Lactic acidosis and severe liver problems, including fatal cases, have been reported with the use of Baraclude, alone or in combination. Contact your physician immediately if you experience nausea, vomiting, or unusual or unexpected stomach discomfort; weakness and tiredness; shortness of breath; weakness in the arms and legs; yellowing of the skin or eyes; or pain in the upper stomach area. These may be early symptoms of lactic acidosis or liver problems.
  
• Some people who have taken medicines like Baraclude have developed serious liver problems called hepatotoxicity, with liver enlargement (hepatomegaly) and fat in the liver (steatosis). Call your healthcare provider right away if; your skin or the white part of your eyes turns yellow (jaundice), your urine turns dark, your bowel movements (stools) turn light in color, you don't feel like eating food for several days or longer, you feel sick to your stomach (nausea) or if you have lower stomach pain. These may be early symptoms of liver problems.
  
• Follow your physician's instructions with respect to high-risk activities such as unprotected sex and the sharing of needles. Baraclude does not reduce the risk of passing hepatitis B virus to others.
  
• It is not known whether Baraclude passes into breast milk and what effect it may have on a nursing baby. Do not take Baraclude without first talking to your doctor if you are breast-feeding a baby.

How do I take Baraclude?

Baraclude is available as 0.5mg tablets and 1mg tablets and should be taken with a full glass of water on an empty stomach - at least 2 hours after a meal and at least two hours before the next meal. Try to take it at the same time every day.

Your dose depends on whether you have been treated for hepatitis B virus infection before and what medicine you took. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Store Baraclude at room temperature away from moisture and heat.

Does Baraclude have any side effects?

There are less serious side effects which may likely occur. Continue taking Baraclude and talk to your doctor if you experience:

• fatigue or tiredness;
• mild nausea, vomiting, diarrhea, or decreased appetite;
• headache;
• dizziness;
• skin rash; or
• insomnia

If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking Baraclude and seek emergency medical attention.

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