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Drug Development
Article Submitted by: Marcia Henin

Thursday, 20 August 2009

Popular drug delivery methods are non-invasive such as through the mouth, topical (on the skin), ocular, vaginal etc. although not all drugs can be transferred via non-invasive methods, such as protein, which requires delivery by injecting it to the blood circulation.

The most popular method of consuming drugs was and still is orally (pills and liquids).

One of the challenging aspects of drug delivery is adjusting these methods to the nature of the drug and the areas and functionalities in the human body that it adheres to tackle.

Therefore, the main goal of drug delivery systems is to deploy medications intact to specific parts in the body via a source that can assist controlling and monitoring its effect and success. Thus when referring to drug delivery systems, scientists are attempting to address the problem of reduced therapeutic effects that are caused due to degradation that occurs in the effect of the drug prior it reaching the desired part in the body. One of the solutions to this problem might have been an attempt to locate different targeted areas in the body to inject the drug to, but it may arouse other problems for different areas in the body react differently to different types of medication. (for instance in the stomach, due to low Ph, a medication can be destroyed).

The world of nanotechnology - polymeric microspheres, polymer micelles and hydrogel-type materials have proven to be greatly efficient in dealing with drug absorption rates, toxicity etc.

The polymeric materials are most popular routes for drug delivery systems research, mainly because the relatively easiness of controlling their chemical and physical properties by researchers.



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